Pose questions to investigate or suggest practical problems to solve in relation to human body systems (e.g., How are the various systems connected to each other? Could one system live without the other systems? If not, why not? Why do we need to eat? Could we breathe without a diaphragm? Which organs work hard during exercise? Why do people sometimes become paralyzed due to an injury?).

Relate body changes, such as acne on the skin and growth of body hair, to human growth and development from birth to puberty.

Represent, physically, dramatically, or visually, the interactions among the skeletal, muscular, and nervous systems that produce movement of the body or parts of the body.

Research how the respiratory, digestive, and circulatory systems work together to move oxygen and nutrients throughout the human body.

Investigate the interdependence between the nervous system and other body systems for reacting to stimuli and controlling body functions.

Explain how the digestive and excretory systems work together to ensure that the body makes use of food that is eaten and disposes of waste.

Propose alterations to the human body that might enable humans to function more effectively to accomplish one or more typical daily tasks.